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CV (cont'd)

7, SELECTED ORIGINAL PAPERS

 

J. Descotes, R. Cadot, J.Cl. Evreux, C. Grenot, C.Y. Cuilleron: Immunological protection against ajmaline toxicity. Journal of Immunopharmacology (1981) 3, 111-117.

J. Descotes, J.Cl. Evreux: Effect of chlorpromazine on contact hypersensitivity to DNCB in the guinea-pig. Journal of Neuroimmunology (1982) 2, 21-25.

J. Descotes, R. Tedone, J.Cl. Evreux: Suppression of humoral and cellular immunity in normal mice by diazepam. Immunology letters (1982) 5, 41-43.

A. Laschi, J. Descotes, P. Tachon, J.Cl. Evreux: Adverse influence of diazepam upon resistance to Klebsiella pneumoniae infection in mice. Toxicology letters (1983) 16, 281-284.

J. Descotes, A. Laschi, P. Tachon, R. Tedone, J.Cl. Evreux: Effects of variations in time and dose of diazepam injection on delayed hypersensitivity. Journal of Immunopharmacology (1983) 4, 279-284.

J. Descotes, R. Tedone, J.Cl. Evreux: Effects of cimetidine and ranitidine on delayed type hypersensitivity. Immunopharmacology (1983) 6, 31-35.

P. Tachon, J. Descotes, A. Laschi-Loquerie, J.P. Guillot, J.Cl. Evreux: Assessment of the allergenic potential of althesin and its constituents. British Journal of Anaesthesia (1983) 55, 515-717.

Y. Benoit, O. Chadenson, B. Ducloux, C.M. Veysseyre, J.P. Bringuier, J.Descotes: Hypersensitivity to Althesin infusion: measurement of complement involvement. Anaesthesia (1983) 38, 1079-1081.

J. Descotes, P. Tachon, A. Laschi-Loquerie, J.Cl. Evreux: Adjuvancy of Cremophor El° in rodents. International Archives of Allergy and Clinical Immunology (1983) 72, 287-288.

A. Laschi-Loquerie, J. Descotes, P. Tachon, J.Cl. Evreux: Influence of lead on hypersensitivity. Experimental study. Journal of Immunopharmacology (1984) 6, 87-93.

J. Descotes, A. Laschi-Loquerie, P. Tachon, J.Cl. Evreux: Comparative effects of various lead salts on delayed hypersensitivity. Journal of Applied Toxicology (1984) 4, 265-266.

J. Descotes, R. Tedone, J.Cl. Evreux: Differential effects of several psychotropic agents on delayed hypersensitivity response in mice. Journal of Neuroimmunology (1985) 9, 81-85.

J. Descotes, P. Andre, R. Tedone, J.Cl. Evreux: Miconazole influence on both cellular immune response and hepatic drug metabolism in mice. Journal of Immunopharmacology (1985) 7, 171-178.

J. Descotes, R. Tedone, J.Cl. Evreux: Immunotoxicity screening of drugs and chemicals: value of contact hypersensitivity to picryl chloride in the mouse. Methods and Findings in Experimental and Clinical Pharmacology (1985) 7, 303-305.

R. Cadot, J. Descotes, C. Grenot, C.Y. Cuilleron, J.Cl. Evreux: Increased paraquat plasma levels in intoxicated mice following anti-paraquat F(ab')2 treatment. Journal of Immunopharmacology (1985) 7, 467-477.

J. Descotes, R. Simonet, J.Cl. Evreux: Influence of several bacterial and viral vaccines on hepatic drug metabolism. Methods and Findings in Experimental and Clinical Pharmacology (1985) 7, 481-483.

A. Eyraud, J.Y. Lombard, J. Descotes, A. Laschi-Loquerie, P. Tachon, C. Veysseyre, J.Cl. Evreux: Effects of josamycin on polymorphonuclear leukocyte chemotaxis. Journal of Antimicrobial Chemotherapy (1986) 17, 763-766.

J.Cl. Evreux, G. Prost, J. Descotes, A. Bergeret: Method for the assessment of diagnosis in toxicology. Regulatory Toxicology and Pharmacology (1987) 7, 169-178.

A. Laschi-Loquerie, A. Eyraud, D. Morisset, A. Sanou, P. Tachon, C. Veysseyre, J. Descotes: Influence of heavy metals on the resistance of mice toward infection. Immunopharmacology and Immunotoxicology (1987) 9, 235-242.

J.Y. Lombard, J. Descotes: Polymorphonuclear leucocyte chemotaxis little affected by three quinolones in vitro. Journal of Antimicrobial Chemotherapy (1987) 4, 614-615.

J. Descotes, A. Guillermin, J.Cl. Evreux: Influence of tetanus and typhoid vaccines on hepatic drug metabolism. Pharmacology (1987) 36, 134-139.

A. Laschi-Loquerie, P. Tachon, C. Veysseyre, J. Descotes: Macrophage migration inhibition test to evaluate the sensitizing potential of drugs in the guinea-pig. Archives of Toxicology (1987) Suppl.11, 325-328.

J. Descotes, R. Tedone, J.Cl. Evreux: Enhancement of antibody response and delayed-type hypersensitivity by thalidomide in mice. Fundamental and Applied Pharmacology (1988) 2, 493-497.

J. Descotes: Identification of Contact Allergens: the Mouse Ear Sensitization Assay. Journal of Toxicology - Cutaneous and Ocular Toxicology (1988) 7, 263-272.

J.P. Brouland, A. Perillat, J.P. Revillard, J. Descotes: Immune competence of valproate-treated mice. Immunopharmacology and Immunotoxicology (1989), 11, 593-602.

A. Bergeret, E. Pouget, R. Tedone, T. Meygret, R. Cadot, J. Descotes: Neutrophil functions in lead-exposed workers. Human and Experimental Toxicology (1990) 9, 231-233.

F. Verdier, M. Virat, J. Descotes: Applicability of the popliteal lymph node assay in Brown-Norway rats. Immunopharmacology and Immunotoxicology (1990) 12, 669-678.

F. Verdier, M. Virat, H. Schweinfurth, J. Descotes: Immunotoxicity of bis(tributyltin)oxide in the rat. Journal of Toxicology and Environmental Health (1991) 32, 307-317.

F. Verdier, F. Condevaux, J. Descotes: Characterization of lymphocyte subsets in Cynomolgus monkeys using flow cytometry. Influence of methylprednisolone. Methods in Toxicology (1991) 1, 263-272.

K. Krzystyniak, J.Ph. Brouland, G. Panaye, C. Patriarca, F. Verdier, J. Descotes, J.P. Revillard: Changes in CD4+and CD8+ lymphocyte subsets by streptozotocin in murine popliteal lymph node (PLN) test. Journal of Autoimmunity (1992) 5, 183-197.

C. Patriarca, F. Verdier, J.Ph. Brouland, J. Descotes: Popliteal lymph node response to procainamide and isoniazid. Role of ß-naphtoflavone, phenobarbitone and S-9 mix pre-treatment. Toxicology Letters (1992) 66, 21-28.

F. Verdier, F. Condevaux, R. Tedone, M. Virat, J. Descotes: In vitro assessment of phagocytosis. Interspecies comparison of chemiluminescence response. Toxicology in vitro (1993) 7, 317-320.

J.P. Brouland, F. Verdier, C. Patriarca, T. Vial, J.Descotes: Morphology of popliteal lymph node responses in Brown-Norway rats. Journal of Toxicology and Environmental Health (1994) 41, 95-108.

C. Patriarca, F. Verdier, J.P. Brouland, T. Vial, J. Descotes: Comparison of popliteal lymph node responses in various strains of rats. Human and Experimental Toxicology (1994) 13, 455-460.

K. Krzystyniak, R. Desjardins, H.M. Thérien, W. Banska, P. Tancrede, J. Descotes: Lymphocyte activation by liposome-trapped streptozotocin in murine popliteal lymph node (PLN) test. International Journal of Immunopharmacology (1994) 16, 817-824.

F. Verdier, I. Chazal, J. Descotes: Anaphylaxis models in the guinea-pig. Toxicology (1994) 93, 55-61.

T. Vial, J. Descotes: Contact sensitization assays. Do they predict the risk for hypersensitivity­? Toxicology (1994) 93, 63-75.

I. Chazal, F. Verdier, M. Virat, J. Descotes: Prediction of drug-induced immediate hypersensitivity in guinea-pigs. Toxicology in vitro (1994) 8, 1045-1049.

F. Verdier, M. Aujoulas, F. Condevaux, J. Descotes: Determination of lymphocyte subsets and cytokine levels in nonhuman primates: cross-reactivity of human reagents. Toxicology (1995) 105, 81-90.

E. Pham, B. Nicolas, T. Vial, J. Descotes:  Modelization of warning procedures to detect the toxic effects of drugs and chemicals to man: application to a sentinel disease programme in immunotoxicology. Toxicology Modelling (1995) 1, 207-218.

R.J. Vandebriel, C. Meredith, M.P. Scott, E. Gleichmann, N. Bloksma, E.H.M. Vant’erve, J. Descotes, H. Van Loveren: Early indicators of immunotoxicity: development of molecular biological test batteries. Human and Experimental Toxicology (1996) 15, Suppl.1, 2-9.

T. Vial, B. Nicolas, J. Descotes: Drug-induced autoimmunity. Experience of the French Pharmacovigilance system. Toxicology (1997) 119, 23-27.

F. Verdier, C. Patriarca, J. Descotes: Autoantibodies in conventional toxicity testing. Toxicology (1997) 119, 51-58.

T. Vial, B. Legrain, J. Carleer, F. Verdier, J. Descotes: The popliteal lymph node assay: results of a preliminary interlaboratory validation. Toxicology (1997) 122, 213-218.

G. Choquet-Kastylevsky, A.L. Souillet, B. Bellemin, S. Ronger, J. Descotes: Pustular eruption following acute mercury exposure. Journal of Environmental Medicine (1999) 1, 55-56.

G. Choquet-Kastylevsky, M-T. Ducluzeau, R. Tedone, J-F. Nicolas, J. Descotes: Increased production of gamma-interferon, but not Il-4 mRNA by streptozotocin in the popliteal lymph node assay. Journal of Applied Toxicology (2000) 146, 73-82.

G. Choquet-Kastylevsky, R. Tedone, M-T. Ducluzeau, J. Kehren, J-F. Nicolas, J. Descotes: The popliteal lymph node response to streptozotocin is under type-1, MHC class-I restricted, CD8+ T-cell control. Toxicology (2000) 119, 183-192.

G. Choquet-Kastylevsky, N. Santolaria, R. Tedone, M. Aujoulat, J. Descotes: Induction of delayed-type hypersensitivity to sulfamethoxazole in mice: role of metabolites. Toxicology Letters (2001) 119, 183-192.

G. Choquet-Kastylevsky, F. Testud, J. Descotes: Occupational contact dermatitis to tetrazepam. Two case reports. Contact Dermatitis (2001) 44: 372.

G. Choquet-Kastylevsky, J. Kanitakis, V. Dumas, J. Descotes, M. Faure, A. Claudy (2001) Eosinophlic fasciitis and simvastatin. Archives of Internal Medicine, 161, 1456-1457.

F. Condevaux, J. Guichard, A. Forichon, M. Aujoulat, J. Descotes: Compared effects of morphine and nickel chloride in vitro on NK cell activity in rats and monkeys. Journal of Applied Toxicology (2001) 21, 431-434.

G. Choquet-Kastylevsky, R. Tedone, J. Descotes: Positive responses to imipramine in the popliteal lymph node assay are due to primary irritation. Human and Experimental Toxicology (2001) 20, 591-596.

G. Ravel, M. Christ, C. Ruat, R. Burnett, J. Descotes: Effects of murine IL-2 in (NZB x NZW) F1 female mice. Immunopharmacology and Immunotoxicology (2002) 24, 409-421.

C. Ruat, L. Faure, G. Choquet-Kastylevsky, G. Ravel, J. Descotes: Tritiated thymidine incorporation does not enhance sensitivity of the popliteal lymph node assay. Toxicology (2003) 188, 29-33.

G. Ravel, M. Christ, P. Liberge, R. Burnett, J. Descotes: Effects of two pediatric vaccines on autoimmune diabetes in NOD mice. Toxicology Letters (2003) 146, 93-100.

G. Ravel, F. Horand, M. Christ, J. Descotes: Autoimmunity, environmental exposure and vaccines: is there a link? Toxicology (2004) 196, 211-216.

G. Ravel, M. Christ, F. Horand, J. Descotes: Cytokine release as an endpoint to improve the sensitivity and specificity of the direct PLNA.  Toxicology (2004) 200, 247-254.

G. Choquet-Kastylevsky, J. Descotes: Popliteal lymph node responses to ethanol and acetone differ from those induced by streptozotocin. Archives of Toxicology (2004) 78, 649-654.

R. Burnett, G. Ravel, J. Descotes: Clinical and histopathological progression of renal and other changes in commercially obtained NZB x NZW kept under normal laboratory condition. Experimental and Toxicologic Pathology (2004) 56, 37-44.

G. Ravel, M. Christ, F. Condevaux, J. Descotes: Trichloroethylene does not accelerate autoimmune diabetes in NOD mice. Journal of Immunotoxicology (2004) 1, 141-148.

J.L. Weaver, J.M. Chapdelaine, J. Descotes, D. Germolec, M. Holsapple, M. Woolhiser, P. Anderson, R. House, H. Lebrec, J. Meade, R. Pieters, K.L. Hastings, J. Dean: Evaluation of a lymph node proliferation assay for its ability to detect pharmaceuticals with potential to cause immune-mediated drug reactions. Journal of Immunotoxicology (2005) 2, 11-20.

A. Henry, B. Charpiat, M. Perol, T. Vial, P. de Saint Hilaire, J. Descotes: Paclitaxel associated hypersensitivity reactions. Assessment of the utility of a test dose program. The Cancer Journal (2006) 12, 237-245.


8. SELECTED REVIEW PAPERS

J.Descotes: Adverses consequences of chemical immunomodulation. Clinical Research Practices and Drug Regulatory Affairs (1985) 3, 45-52.

J.Descotes: Immunomodulating agents and hepatic drug metabolizing enzymes. Drug Metabolism Reviews (1985) 16, 175-183.

J.Descotes: Immunotoxicology: health aspects and regulatory issues. Trends in Pharmacological Sciences (1986) 7, 1-4.

T.Vial, J.Descotes: Clinical Toxicity of Interleukin-2. Drug Safety (1992) 7, 417-433.

J.Descotes: The popliteal lymph node assay: a tool for studying the mechanisms of   drug-induced autoimmune disorders. Toxicology letters (1992) 64/65, 101-107.

T.Vial, J.Descotes: Clinical toxicity of the interferons. Drug Safety (1994) 10, 115-150.

J.Descotes, Th.Vial: Immunotoxic effects of xenobiotics in humans: a review of current evidence. Toxicology in vitro (1994) 8, 963-966.

T.Vial, J.Descotes: Immune-mediated side-effects of cytokines in man. Toxicology (1995) 105, 31-57.

T.Vial, J.Descotes: Clinical toxicity of cytokines used as hemopoietic growth factors. Drug Safety (1995) 13, 371-406.

J.Descotes, B.Nicolas, E.Pham, T.Vial: Sentinel screening in human immunotoxicology. Archives of Toxicology (1996) Suppl. 18, 29-34.

J.Descotes, B.Nicolas, T.Vial, J.F.Nicolas: Biomarkers of immunotoxicity in man. Biomarkers (1996) 1, 77-80.

T.Vial, B.Nicolas, J.Descotes: Clinical immunotoxicology of pesticides. Journal of Toxicology and Environmental Health (1996) 48, 215-229.

J.Descotes, C.Patriarca, T.Vial, F.Verdier: The popliteal lymph node assay in 1996. Toxicology (1997) 119, 45-49.

J.Descotes Regulating immunotoxicity evaluation: issues and needs. Archives of Toxicology (1998) 20, Suppl, 293-299.

G.Choquet-Kastylevski, J.Descotes: Value of animal models for predicting hypersensitivity reactions to medicinal products. Toxicology (1998) 129, 27-35.

J.Descotes: Integrating immunotoxicity with other biological systems in preclinical evaluation: a perspective. Toxicology (2000) 142, 157-160.

T.Vial, G.Choquet-Kastylevsky, Ch.Liautard, J.Descotes: Endocrine and neurological adverse effects of the therapeutic interferons. Toxicology (2000) 142, 161-172.

J.Descotes, G.Choquet-Kastylevsky, E.Van Ganse, T.Vial: Responses of the immune system to injury. Toxicologic Pathology (2000) 28, 479-481.

J.Descotes: Autoimmunity and toxicity testing. Toxicology Letters (2000) 112/113, 461-465.

G.Choquet-Kastylevsky, T.Vial, J.Descotes: Diagnosis of drug allergy in humans: possibilities and pitfalls. Toxicology (2001) 158, 1-10.

J.Descotes, G.Choquet-Kastylevsky: The Gell and Coombs classification: is it still valid? Toxicology (2001) 158, 43-49.

G.Choquet-Kastylevsky, T.Vial, J.Descotes: Allergic adverse reactions to sulfonamides. Current Allergy and Asthma Reports (2002) 2, 16-25.

J.Descotes, G.Choquet-Kastylevsky, G.Ravel, C.Ruat: Predicting the risk of autoimmunity and hypersensitivity post-vaccination. Toxicology (2002) 174, 45-51.

T.Vial, G.Choquet-Kastylevsky, J.Descotes: Adverse effects of immunotherapeutics involving the immune system. Toxicology (2002) 174, 3-11

K.Cederbrant, M.Marcusson-Ståhl, F.Condevaux, J.Descotes: NK-cell activity in immunotoxicity evaluation of drugs. Toxicology (2003) 185, 241-250.

T.Vial, J.Descotes: Immunosuppressive drugs and cancer. Toxicology (2003) 185, 229-240.

J.Descotes: Importance of immunotoxicity in safety assessment: a medical toxicologist's point of view. Toxicology Letters (2004) 149, 103-108.

T.Vial, J.Descotes: Autoimmune diseases and vaccination. European Journal of Dermatology (2004) 14, 86-90.

J.Descotes: Role of immunotoxicology in the safety assessment of drugs. Drug Safety (2005) 28: 127-136.

G.Ravel, J.Descotes: The popliteal lymph node assay: facts and perspectives. Journal of Applied Toxicology (2005) 25, 451-458.

M.Ban, A.Braun, S.Casati, E.Corsini, J.Dastych, J.Descotes, A.Gennari, L.Gribaldo, T.Hartung, R.Hooghe-Peters, R.House, M.Pallardy, R.Pieters, L.Reid, H.Tryphonas, E.Tschirhart, H.Tuschl, R.Vandebriel: The use of in vitro systems for evaluating Immunotoxicity. Journal of Immunotoxicology (2005) 2, 61-83.

J.Descotes, G.Ravel: Role of NK cells in immunotoxicity: an update. Expert Review of Clinical Immunology (2005) 1, 605-610.

J.Descotes: Methods of evaluating immunotoxicity. Expert Opinion on Drug Metabolism and Toxicology (2006) 2, 249-260.

T.Vial, J.Descotes: Autoimmunity and toxic exposures: overview of the current clinical evidence. Perspectives in Experimental and Clinical Immunotoxicology (2007) 1, 3-14.

G.Ravel, J.Descotes: Animal models of autoimmune diseases and their use in safety evaluation studies. Perspectives in Experimental and Clinical Immunotoxicology (2007) 1, 31-40.

J.Descotes, C.Payen, T.Vial: Pseudo-allergic drug reactions with special reference to direct histamine release. Perspectives in Experimental and Clinical Immunotoxicology (2007) 1, 41-50.